Center for Open Research Resources and Equipment (COR²E)

The Microbial Analysis, Resources and Services (MARS) facility supports research specializing in the analysis of microbial samples and high-throughput processing of nucleic acids. Examples include the characterization of microbiomes, sequencing of small genomes, 96-well and 384-well PCR setup or DNA quantification and other automated liquid handling applications.

The Nuclear Magnetic Resonance Facility recognizes the important role that NMR plays in molecular structure determination and conformational analysis for research projects engaging chemical synthesis, chemical mixture characterization, drug design, intermolecular interaction studies, protein and nucleic acid characterization. The joint NMR Facility of COR²E and the Department of Chemistry offers several solution-state NMR instruments on a fee-for-use basis. The instrumentation serves the high-resolution research needs for investigators from the University of Connecticut and nearby colleges and companies.

The Proteomics & Metabolomics Facility implements ultra-high performance liquid chromatography (UPLC) coupled to high resolution mass spectrometry (MS) to unambiguously identify proteins, peptides and small molecules in complex mixtures.

The Statistical Consulting Services (SCS) provides advice on statistical problems arising in the preparation of studies, the analysis of data and the interpretation of results. It provides a center for discussion on research problems and methodological advances in statistics and probability.

Mechanical/Glass: Design & Fabrication Facility supports academic research through consultation, engineering, manufacturing, design, and repairs. Within the facility, there are complete departments for working with glass, metal, plastics, and other materials. Skilled technicians design, fabricate, or repair complex mechanical instruments and glassware, and carry out jobs in precision machining, MIG and TIG welding, woodworking, sheet metal, and plexiglass fabrication.

Flow Cytometry Facility provides investigators with our expertise and sophisticated instruments for the analysis of cells or particles based on size, internal complexity, and fluorescent signals. Cytometers allow simultaneous analysis of multiple properties of cells or particles and provide information about both single cells and populations. The heterogeneous cells and populations can be identified and quantified. Selected cells or particles can also be physically sorted to obtain pure populations for further analysis or subsequent culture and functional study.

The Electrical/Electronics: Technology and Repair facility supports academic research and administrative activities through consultation, support, development, and repairs. Services include computer repair, lab equipment repair, electrical and electronic support, and office equipment repairs.

The Biophysics Facility consists of microcalorimetry (isothermal titration calorimetry and differential scanning calorimetry) and microscale thermophoresis. These approaches support research specializing in the study of characteristics of molecules and the interaction between molecules. These biophysical characteristics are of great interest to many biological, pharmaceutical, and chemical research questions.

The BioSupply Facility provides biological research supply services and stock room capabilities. The mission of the facility is to simplify research supply ordering and receiving. In addition to maintaining a constant stock of commonly utilized consumables, the facility works with a wide variety of vendors to provide a cost savings to faculty on equipment and reagents.

The Advanced Light Microscopy Facility provides access to advanced imaging technology in order to promote innovation and cross-disciplinary interaction. The facility houses a number of laser scanning confocals, as well as systems for widefield imaging and total internal reflection microscopy.