Don't think a year of madness has stopped our facilties! COR²E has continued to support UConn, create world-class research, and build community connections during the pandemic; check out this newsletter for the inside scoop.
Attachment: Spring 2021 Newsletter
In conjunction with the ramped reopening of UConn research, our COR²E managed facilities have officially reopened. Due to unique operational differences between facilities, however, the degree of service provided will differ from one facility to another. In an effort to maintain the safety of our users and staff (particularly because our facilities are utilized by hundreds of students and faculty across UConn), it is imperative that users adhere to safety policies outlined by the institution/state (logging presence, PPE, maintaining distance, etc.) as well as those procedures that have been created by the specific facility.
If your lab has received approval from the OVPR to resume research activity, and you wish to utilize one of the COR²E managed facilities, please reach out to the respective facility director who can provide guidance on policies/procedures and scheduling (contact information can be found in the resources section of this website).
There will undoubtedly be challenges associated with reopening the facilities, and it is conceivable that they will not be back to providing 100% of their former services for some time. That said, the facilities are committed to supporting the UConn research community in its important work, and are striving to accommodate the varying research needs of our faculty. Please try to bear with them.
Finally, as always, if there are ever any non facility-specific questions that arise, please do not hesitate to reach out to Dan Schwartz (email@example.com).
We look forward to working with everyone again.
As a result of the Governor's Executive Order and the latest directive at the University to ramp down all non-critical research, and for the safety of our users and staff, the following COR²E managed facilities will be closed for operation starting on Monday (3/23/20): Advanced Light Microscopy, BioSupply, Biophysics, Electrical/Electronics: Technology & Repair, Flow Cytometry, Mechanical/Glass: Design & Fabrication, Microbial Analysis, Resources, and Services, Nuclear Magnetic Resonance, and Proteomics & Metabolomics. Our Statistical Consulting Service will remain open as all consultations are being carried out remotely. Doors to these facilities will remain locked until further institutional guidance is provided.
Those performing critical (i.e., COVID-19 related) research that wish to utilize the COR²E managed facilities should contact the respective facility director to make special arrangements.
As our BioSupply facility will be closed starting on Monday (3/23/20), all orders to the TLS, PBB, and BPB buildings that were previously delivered through the BioSupply facility will be diverted to the Central Warehouse for delivery; however researchers should take care not to order non-critical reagents at this time (in part because refrigeration and freezer capabilities in the Central Warehouse are limited).
It is important to note that our facility directors are still working remotely - this is an opportune time to schedule a teleconference to plan out future experiments or analyze existing data.
If there are any facility-specific questions please reach out to the appropriate facility director, and for all other questions please feel free to reach out to Dan Schwartz.
Stay healthy and safe everyone.
The University of Connecticut Proteomics & Metabolomics Facility (PMF) is hiring an Facilities Scientist II to assist the Facility Director with quantitative proteomics and metabolomics analysis using advanced mass spectrometry instrumentation and leading bioinformatics software. The PMF opened in 2017 as the University of Connecticut’s first proteomics-focused full service core facility. The laboratory exists to provide fully customized analysis to more than 70 faculty across multiple UConn campuses and at other regional academic and industry research institutions. The position will be a full-time appointment and will provide a unique opportunity to work in a rapidly growing and highly productive core facility at a large research university currently ranked in the top 25 of all public universities in the U.S. The diverse research community at UConn participates in both basic science and clinical research that provides opportunities for a wide variety of innovative proteomics and metabolomics analysis. For more information on the position and to apply, visit https://jobs.uconn.edu/en-us/job/494369/facilities-scientist-2.
Our intention is to keep core research facilities managed by COR²E operational at this time. That said, many of our facilities have very limited staffing (some of which include student employees) and as such, may necessitate a reduction in services or even closure. Additionally, many of our core facilities rely on equipment and services from external vendors who may also experience delays that could translate to our internal services. Facilities may also choose to limit/stagger usage of equipment to reduce contact between facility users. Users of the facilities are encouraged to plan their experiments accordingly and visit their respective core facility homepages and/or contact facility directors for the most current information (though changes to services and schedules will also be communicated to existing facility users via email). Finally, as shared communal facilities, we will be working to keep shared equipment spaces as disinfected as possible, but we also ask for users’ help in doing so (washing hands before using shared equipment, staying home at any sign of illness, etc.) If additional updates are needed, they will be posted here. Stay healthy everyone!
Come join us for our first ever symposium highlighting the facilities in COR²E on Monday 11/19 from 8:45am to 5pm in Pharm/Bio 131. We'll have informational talks by the facility directors, research talks by grad students and post-docs, lunch in the afternoon, and an open bar at the end of the day!
Detailed flyer/schedule attached.
Attachment: 2018 COR²E Symposium Flyer/Schedule
We've been meaning to do this for a while and have finally been able to put together the inaugural issue of our COR²E newletter. We're not yet sure how often we'll put these out, though it will probably be dictated by having enough new and useful information to convey. Worth noting, this issue was designed by Squared Labs (former) undergrad team member Samantha Heanue, who graduated this past spring. As always, let us know what you think.
Attachment: COR²E Newsletter Fall 2018
COR²E is pleased to welcome Mr. Scott LaForest as a senior machine shop engineer in our Mechanical/Glass: Design & Fabrication facility. Scott has an outstanding background in precision machining and toolmaking and comes to us most recently from the Tennessee College of Applied Technology where he singlehandedly implemented a new course of study in Machine Tool Technology. Scott will be working alongside machinist wizard Mark Drobney, director of the facility. Needless to say, we're very excited to have Scott on our COR²E team!
The COR²E Flow Cytometry Facility has finalized the installation and validation of a new Biosafety Level 2 (BSL2) enclosure for the FACSAria II cell sorter. The enclosure, which is located at the rear of room G05 in Bio/Physics, allows researchers on the Storrs campus to sort human samples or those with viral vectors (finally!). Those interested in utilizing its capabilities for their research should contact Flow Cytometry Facility director Dr. Wu He (firstname.lastname@example.org).
Squared Labs' extremely talented undergraduate lead illustrator, Hayley Joyal, created a visually stunning watercolor to depict concepts from Brent Graveley's recently accepted Molecular Cell paper. The illustration was selected for the cover of the issue!
See tweet about it here.
Remember to contact us at email@example.com the next time you have a manuscript accepted and the journal makes a cover art request.
Dr. Kendra Maas, Director of the UConn Microbial Analysis, Resources and Services (MARS) facility was highlighted today for her work mentoring a student on research into microbial communities in aquaponic systems. The work at UConn's Spring Valley Farm lays the preliminary groundwork for a future microbial aquaponics testing service that may be offered through the MARS facility to the aquaponics community across the state.
Moving forward the drop-off location for all scientific glassware repairs will be on the large metal shelf across from the machine shop (room A007) in the Chemistry building. Place your clean, broken glassware into a sturdy cardboard box along with a sheet containing the PI name, contact name, phone number, email, and any specific instructions for our glassblower Daryl Smith (firstname.lastname@example.org). Please use bubble wrap or paper to make sure the boxes can be transported by car without further damage to your glassware.
The boxes will be picked up at regular intervals (~1 pickup per week, more if needed) and repaired glassware will be placed back on the shelf when completed. Users will be notified when the glassware was repaired and/or is back. The machine shop engineer from Chemistry, Dan Daleb (email@example.com), has kindly agreed to keep an eye on the shelf. If you have especially valuable items to send to Daryl, talk to Dan and he will safeguard it for you.
Users may also drop off their glassware at the Mechanical or Electrical COR²E facilities in Thomson Hall on the depot campus (at 30 Ahern Lane).
Finally, please contact Daryl directly to discuss any special projects. Daryl is available to meet either in the Chemistry building or on the depot campus.
The COR²E Advanced Light Microscopy Facility recently acquired a new scientific CMOS camera that is extremely sensitive and fast.
Here's what Facility Director Dr. Chris O'Connell wrote about it:
The Photometrics Prime 95B camera has a quantum efficiency (QE) of 95% and can acquire images at hundreds of frames per second. We have already done some experiments at >700 fps. The camera is mounted on the Andor system and can be used for imaging with transmitted light (brightfield, DIC, phase contrast), TIRF, and widefield fluorescence. This system also has incubation for imaging live specimens. If you have research that can benefit from very high temporal resolution, let me know and we can discuss the details. Full system specs are here: https://confocal.uconn.edu/andor/.
If you've been on this website previously you have probably noticed that it has been redesigned, if you haven't, well, then welcome to our newly designed website! The content has not changed, but we hope that you find navigating the new site to be an enjoyable and informative experience. As always, if you have questions/comments please get in touch.
[squared labs] (https://squaredlabs.uconn.edu), a subunit of COR²E, is launching a new pilot specifically for the purpose of creating high quality research journal cover art.
So - the next time your paper gets accepted and the journal sends out a request for cover art, please refrain from opening Powerpoint, and contact us instead. We'll put you in touch with our phenomenal team of student illustrators who will work with you to create something both informative and beautiful. And best of all, COR²E is subsidizing it entirely (at least for the time being) so it will cost you nothing! The plan is to eventually provide this service also for journal/grant figures, but for now we are starting with journal cover art.
The new Proteomics & Metabolomics Facility (http://proteomics.uconn.edu) led by Facility Director Dr. Jeremy Balsbaugh has been fully operational for roughly 2 months now, and has been working with a significant number of faculty across the Storrs and UCH campuses. Dr. Balsbaugh will be providing a seminar to outline the services and capabilities of the new facility.
Here are the details:
Title: Biological Mass Spectrometry at UConn: An Introduction to the New COR²E Proteomics & Metabolomics Facility
Date/time: Thursday, November 9th at 3:30pm
Location: Pharmacy/Biology Building Room 131 (Storrs campus)
We look forward to seeing you there!
The [squared labs] subunit of COR²E has launched GrantTrails, a new website aimed at visualizing where grant funds are expended throughout the state. People tend to assume that grant funds stay within an institution when the reality is that most of the funds support people and businesses throughout our state. Have a look and let us know what you think (link below).
UConn Today story posted here (http://today.uconn.edu/2017/10/website-breaks-statewide-benefit-uconn-research-funding/).
The Center for Open Research Resources and Equipment has officially launched a subunit called [squared labs]. [squared labs] is comprised of top undergraduate student web developers, designers, and content specialists aimed at building beautiful and interactive web software to support UConn research. The group is located in BPB G01 (the enigmatic room with the [squared labs] decal on the door). We've also put together a (very preliminary) website - see link below.
The Advanced Light Microscopy Facility has completed its move from the 3rd floor of the Biology/Physics building to the ground floor of the same building (room G05D). Please contact Dr. Chris O’Connell (firstname.lastname@example.org) for all questions related to the facility.
The UConn Microbial Analysis, Resources, and Services (MARS) Facility has completed its move from Beach Hall to the new Engineering and Sciences Building (ESB). Feel free to stop by to check out their beautiful new space on the 3rd floor. For information regarding the MARS Facility please contact Dr. Kendra Maas (email@example.com), visit the MARS website (http://mars.uconn.edu), or follow MARS on Twitter (@UConnMARS).
We're excited to announce that the UConn Proteomics & Metabolomics Facility (UConn PMF) is officially open and accepting samples for analysis.
The facility implements high resolution mass spectrometry (MS) technology and currently has two state-of-the-art instruments (a Thermo Scientific Q Exactive HF and Waters Synapt G2Si) capable of accurately measuring masses of proteins, peptides, and small molecule metabolites in complex mixtures. Both instruments are coupled to high resolution liquid chromatograph (LC) instruments to provide solution-based separations prior to mass analysis. This technology allows researchers to identify and quantify thousands of analytes in a single LC-MS run.
For more information (including rates/services) visit the COR²E website (http://core.uconn.edu/resources/proteomics) or UConn PMF’s brand new website (http://proteomics.uconn.edu). Dr. Balsbaugh can also be directly contacted at firstname.lastname@example.org.
It is worth noting that support for the creation of the Proteomics & Metabolomics Facility was truly institutional, and was made possible by funding contributions/pledges from the Office of the Provost (via a 2015 Academic Plan award), the Office of the Vice President for Research, the College of Liberal Arts and Sciences, the School of Pharmacy, the College of Agriculture, Health and Natural Resources, the School of Engineering, the Department of Molecular and Cell Biology, the Department of Physiology and Neurobiology, the Department of Chemistry, the Department of Pharmaceutical Sciences, the Department of Chemical and Biomolecular Engineering, and the Department of Plant Sciences and Landscape Architecture.
Look above, you'll see 2 new buttons - "commercialize your research" and "apply for travel funds". Click on them and see what happens...
The Flow Cytometry Facility has completed its permanent move from Biology/Physics Building room 303 to Biology/Physics Building room G05. All facility services have resumed as normal. For questions (including after hours access) please contact Flow Cytometry Facility Director Dr. Wu He (email@example.com).
The COR²E student software developers have yet again built a new website - this time for OVPR/AAUP travel funding requests. If you like it let us know, if not, feel free to keep it to yourself! If you find bugs email Courtney (firstname.lastname@example.org). All other questions about the program can be directed to Matt Mroz (email@example.com).
The COR²E student software developers have built a new website for the UConn Technology Incubation Program. Check it out to learn how UConn’s state-of-the-art incubation program helps transform research into startups ready to transform their markets.
Dr. Heidi Erlandsen, a former faculty member at Stockholm University and the University of Alabama and most recently a Research Specialist in the laboratory of Dr. Jim Cole (MCB), begins a new position today as the Director of the Biophysics Facility. Dr. Erlandsen is a highly skilled crystallographer and biophysicist more generally. The COR²E Biophysics Facility represents the merger of three former facilities (analytical ultracentrifugation, X-ray crystallography, and microcalorimetry). Please contact Dr. Erlandsen (firstname.lastname@example.org) for assistance with any biophysics research needs.
Moving forward all scientific glassblowing services will be carried out from the Yale University Glass Shop. Daryl Smith, the scientific glassblower, will pick up and deliver to UConn on Wednesdays at 3pm at the Chemistry Department Glass Shop (R010). Users are welcome to contact Daryl to schedule an appointment to discuss their glass needs in person when he is on campus. Alternatively, users may also visit Daryl at the Yale University Glass Shop (Sterling Chemistry Building, room 14, 225 Prospect Street, New Haven). Daryl Smith contact info: email: email@example.com phone: 203.432.3919
We just added this new section to our website. Please check back often to get the latest news and announcements from the Center for Open Research Resources and Equipment.
The Microbial Analysis, Resources, and Services Facility has moved (actually back in October, but we didn't have a news section back then!) to Beach Hall (room 201 in the CGI) from its previous location in Bio/Physics G05. The same great services are still provided, or so we hope... Contact Dr. Kendra Maas (firstname.lastname@example.org) with any questions.
Sanger sequencing services have moved (physically and administratively) from CORE to the Center for Genome Innovation (CGI). Existing rates and services have remained unchanged, though you should check out the CGI website to learn more (including newly added services). Sample drop off at the old location (Bio/Physics G05) is still available via dropbox. Contact Dr. Bo Reese (email@example.com) with any questions.
The BioSupply and Sanger Sequencing Facility has been renamed simply the BioSupply facility and has moved from Bio/Physics G05 to Torrey Life Sciences 175 (Ken Bernier's former Biology Stock Room space). In addition to providing the previous services of the former BBC DNA Biotechnology Biology Supply Center program and the BCS Biology Stock Room, the new BioSupply facility will be expanding its services in the coming months and will do its best to save faculty time and money when it comes to ordering reagents/equipment/consumables/etc. Please contact Mr. Xiaoyang Liu (firstname.lastname@example.org) with questions about the new facility.
As of the new year, the Animal Cell Culture Facility is officially closed. Former users who have not yet picked up their frozen cells (or wish to continue storing their cells) may do so by contacting Dr. Steve Geary (email@example.com), Head of the Pathobiology and Veterinary Science Department, who is administering the liquid nitrogen dewars formerly held in the ACC Facility. Users who are interested in purchasing cell culture media formerly offered by the facility should contact Xiaoyang Liu (firstname.lastname@example.org) of the BioSupply Facility who is presently working with vendors for a discounted cell culture media solution.
We are very pleased to announce that Dr. Jeremy Balsbaugh, presently the Director of the Mass Spectrometry Core at University of Colorado-Boulder, has formally accepted the offer to become the Director of the (soon to be formally established) Proteomics & Metabolomics Facility at UConn. Dr. Balsbaugh will be arriving on campus in early March and will start the process of establishing the facility and its services. The Proteomics & Metabolomics facility will be based out of the main CORE space in Bio/Physics G05 on the Storrs campus, but will serve users across all UConn campuses.