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The Core Incentive Plan (CIP) is back for 2025!

CIP is an internal funding initiative administered by UConn OVPR that provides seed funding to faculty from UConn Storrs to be allocated for research projects that specifically engage UConn's world-class diverse core facilities.

Learn more about the CIP

Laboratory of Mass Spectrometry and Omics Analysis

Laboratory of Mass Spectrometry and Omics Analysis

The Laboratory of Mass Spectrometry and Omics Analysis offers seven mass spectrometers. The facility also provides a wide variety of analytical services.

Visit Facility Homepage

Contacts

Staff

Adam Graichen, Ph.D.

Facility Manager
adam.graichen@uconn.edu
860.486.5839

Faculty Scientific Advisers

Xudong Yao, Ph.D.

Associate Professor
x.yao@uconn.edu
860.486.6644

Location

Campus Address

Chemistry Building, Room 403
Storrs Campus

Mailing Address

55 North Eagleville Road
Storrs CT 06269-6030

Instrumentation

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DRAT/Electrospray-Time-of-Flight (DART-TOF) Mass Spectrometer

  • AccuTOF-DART (JEOL)
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Electrospray/Nanospray Quadrupole-Time-of-Flight Mass Spectrometer

  • QStar Elite (AB Sciex)
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Gas-Phase Chromatography-Electron Impact -Quadrupole Mass Spectrometer

  • GC-MSD 5975 (Agilent)
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Triple Quadrupole Mass Spectrometer: Quantiva

  • Quantiva (ThermoFisher)
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Triple Quadrupole Mass Spectrometer: 4000 QTrap

  • 4000 QTRAP (AB Sciex)
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Triple Quadrupole Mass Spectrometer: API 2000

  • API 2000 (AB Sciex)
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Triple Quadrupole Mass Spectrometer: Quattro II

  • Quattro-II (Waters)

Services and Rates

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Biopolymers: Proteins

Services include:

  • LC-MS of purified proteins for molecular weight determination
  • LC-MS of protein mixtures
  • LC-MS/MS of single protein digest

For detailed information: https://msomics.chemistry.uconn.edu/biopolymers/

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Biopolymers: Nucleic Acids

Services include:

  • LC-MS for molecular weight measurements
  • LC-MS/MS for nucleic acid modifications

For detailed information: https://msomics.chemistry.uconn.edu/biopolymers/

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Organics Analysis

Analysis services provided by MS Specialists include:

  • Hi-Res on QStar Elite Mass Spectrometer
  • Hi-Res on DART-TOF Mass Spectrometer
  • LC-MS on Quattro II
  • LC-MS/MS on API 2000

For detailed information: https://msomics.chemistry.uconn.edu/organics/

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Proteomics Services

Services include:

  • Analysis of proteome samples separated by SDS-PAGE on LC-MS/MS on QStar Elite; data analysis via Mascot
  • Proteome samples as protein mixtures

For detailed information: https://msomics.chemistry.uconn.edu/omics/