Laboratory of Mass Spectrometry and Omics Analysis

Laboratory of Mass Spectrometry and Omics Analysis

The Laboratory of Mass Spectrometry and Omics Analysis offers seven mass spectrometers. The facility also provides a wide variety of analytical services.

Visit Facility Homepage

Contacts

Staff

Adam Graichen, Ph.D.

Facility Manager
adam.graichen@uconn.edu
860.486.5839

Faculty Scientific Advisers

Xudong Yao, Ph.D.

Associate Professor
x.yao@uconn.edu
860.486.6644

Location

Campus Address

Chemistry Building, Room 403
Storrs Campus

Mailing Address

55 North Eagleville Road
Storrs CT 06269-6030

Instrumentation

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DRAT/Electrospray-Time-of-Flight (DART-TOF) Mass Spectrometer

  • AccuTOF-DART (JEOL)
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Electrospray/Nanospray Quadrupole-Time-of-Flight Mass Spectrometer

  • QStar Elite (AB Sciex)
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Gas-Phase Chromatography-Electron Impact -Quadrupole Mass Spectrometer

  • GC-MSD 5975 (Agilent)
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Triple Quadrupole Mass Spectrometer: Quantiva

  • Quantiva (ThermoFisher)
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Triple Quadrupole Mass Spectrometer: 4000 QTrap

  • 4000 QTRAP (AB Sciex)
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Triple Quadrupole Mass Spectrometer: API 2000

  • API 2000 (AB Sciex)
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Triple Quadrupole Mass Spectrometer: Quattro II

  • Quattro-II (Waters)

Services and Rates

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Biopolymers: Proteins

Services include:

  • LC-MS of purified proteins for molecular weight determination
  • LC-MS of protein mixtures
  • LC-MS/MS of single protein digest

For detailed information: https://msomics.chemistry.uconn.edu/biopolymers/

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Biopolymers: Nucleic Acids

Services include:

  • LC-MS for molecular weight measurements
  • LC-MS/MS for nucleic acid modifications

For detailed information: https://msomics.chemistry.uconn.edu/biopolymers/

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Organics Analysis

Analysis services provided by MS Specialists include:

  • Hi-Res on QStar Elite Mass Spectrometer
  • Hi-Res on DART-TOF Mass Spectrometer
  • LC-MS on Quattro II
  • LC-MS/MS on API 2000

For detailed information: https://msomics.chemistry.uconn.edu/organics/

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Proteomics Services

Services include:

  • Analysis of proteome samples separated by SDS-PAGE on LC-MS/MS on QStar Elite; data analysis via Mascot
  • Proteome samples as protein mixtures

For detailed information: https://msomics.chemistry.uconn.edu/omics/