Biomarkers and Preclinical Models Research Core

Biomarkers and Preclinical Models Research Core

The Biomarkers and Preclinical Models Research Core assists investigators wishing to add biomarkers to geriatric research studies. It also develops and maintains mouse models needed for preclinical testing of interventions targeting specific geriatric conditions.

Contacts

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George Kuchel

Professor
kuchel@uchc.edu
860.679.3956
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Laura Haynes, Ph.D.

Professor
lhaynes@uchc.edu
860.679.8431
Whitney Wolf

Whitney Wolf

Core Manager
wwolf@uchc.edu
860.679.1339

Services & Rates

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Mouse Models

Mouse models are developed and maintained for use in preclinical testing of interventions targeting specific geriatric conditions. Mouse strength and mobility, body composition, cognitive testing, bone density, host defense and bladder function can all be assessed.

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Biomarkers

This facility assists investigators wishing to add biomarkers to geriatric research studies.  Biomarker capacities include a BioRad Magpix Bioplex system, quantitative PCR and ELISA. Additional analytic capacities are also available in terms of measurement of dietary antioxidants and phytochemicals (e.g., polyphenols and metabolites), lipids, oxidative stress markers, and metabolomics.

Campus Address

UConn Health

Mailing Address

263 Farmington Avenue, MC-1835
Farmington, CT 06030-5215